I’ve been using Plasma 6 and Wayland since Plasma 6 was stable. IMO, you shouldn’t have any issues using Wayland in todays landscape.
It has gotten a LOT better, but there are still niche cases.
I have a TV hooked up via HDMI and can only output 4K30Hz on Wayland and my system starts chugging. With X11 I can do 60Hz no problem.
I will need to take a hard look if I will go for Nvidia or AMD when I build a new system in a few weeks/months.
A new PC upgrade is on my list after building a NAS and I have almost the same parts on my list, just as regular ATX. Maybe look for a good deal on a WD Black SN850X as a small upgrade over the Crucial NVME.
I will be going for the same cooler as well, since I don’t see the value in an AIO solution for non high-end CPU. The downsides outweigh the superior cooling at that wattage IMO.
I actually asked in the TrueNAS forum about this idea. According to some knowledgeable users this might work. For anyone interested, details here. The next major release (planned for end of October), should make this easier.